Research suggests that depression doesn’t spring from simply having too much or too little of certain brain chemicals. Rather, there are many possible causes of depression, including faulty mood regulation by the brain, genetic vulnerability, stressful life events, medications, and medical problems.
What is the biological basis of depression?
The biological factors that might have some effect on depression include: genes, hormones, and brain chemicals. Depression often runs in families, which suggests that individuals may inherit genes that make them vulnerable to developing depression.
Is there a biological marker for depression?
Currently, the diagnosis of major depressive disorder (MDD) mainly relies on clinical examination and subjective evaluation of depressive symptoms. At present there is no approved biomarker as part of the diagnostic criteria for any psychiatric disorder (1-3).
What is the number one cause of depression?
Research suggests that continuing difficulties – long-term unemployment, living in an abusive or uncaring relationship, long-term isolation or loneliness, prolonged work stress – are more likely to cause depression than recent life stresses.
Is depression biological or environmental?
The depression gene
Scientists believe that as many as 40 percent of those with depression can trace it to a genetic link. Environmental and other factors may make up the other 60 percent.
What are the most reliable biological depression markers?
Brain-derived neurotrophic factor (BDNF) is the most frequently studied of these.
Can a blood test tell if you have depression?
Diagnosing depression: there is no blood test.
Are there biomarkers for bipolar disorder?
Biomarkers can be used in medicine for diagnosis, prognosis, or treatment guidance. In bipolar disorder, biomarkers have been studied not only to identify specific features associated with the diagnosis but also to detect illness activity related to mood episodes.
Is depression genetic or learned?
Depression is known to run in families, suggesting that genetic factors contribute to the risk of developing this disease. However, research into the genetics of depression is in its early stages, and very little is known for certain about the genetic basis of the disease.
What happens to brain during depression?
There’s growing evidence that several parts of the brain shrink in people with depression. Specifically, these areas lose gray matter volume (GMV). That’s tissue with a lot of brain cells. GMV loss seems to be higher in people who have regular or ongoing depression with serious symptoms.
What hormone is released during depression?
How Does Your Body Use Serotonin? Serotonin is in the brain. It is thought to regulate mood, happiness, and anxiety. Low levels of serotonin are linked to depression, while increased levels of the hormone may decrease arousal.