It concluded that taking fluoxetine in the first trimester of pregnancy increased the risk of birth defects in the child by 18%. These defects might include the child being born with spina bifida, or having an extra ureter (the duct though which urine passes from the kidney to the bladder).
What birth defects can Prozac cause?
In previous studies, fluoxetine appeared to be linked with four types of birth defects. In this study, researchers observed fluoxetine to be linked with these two birth defects: Heart defects with obstruction of the right ventricular outflow tract. Craniosynostosis, a birth defect of a baby’s skull.
Does Prozac increase risk of miscarriage?
June 2, 2010 — A Canadian study of more than 5,000 women shows an association between taking antidepressants, particularly the selective serotonin reuptake inhibitors (SSRIs) such as Paxil, Prozac, and Zoloft, and an increased risk for miscarriage.
Does Prozac in pregnancy cause autism?
The increased risk was limited to a family of antidepressants known as selective serotonin reuptake inhibitors (SSRIs) that includes drugs such as Paxil, Prozac, Zoloft and Celexa. SSRIs were linked to a more than doubled risk of autism.
Why you shouldn’t take antidepressants while pregnant?
The biggest concern is typically the risk of birth defects from exposure to antidepressants. Overall, the risk of birth defects and other problems for babies of mothers who take antidepressants during pregnancy is very low. However, some antidepressants are associated with a higher risk of complications for your baby.
Does Prozac cross the placenta?
Studies using animal models have demonstrated that fluoxetine not only crosses the placenta, but also accumulates within fetal brain tissue within 5 hours after drug administration [45, 46].
How long should you be off Prozac before getting pregnant?
If the consensus is that you should wean yourself off your meds or try different kinds, start at least three months before you start trying to conceive so you’ve got plenty of time to see how it goes.
What category is Prozac in pregnancy?
Safety of Psychiatric Medications During Pregnancy and Lactation
|Drug||FDA pregnancy category*|
What is Pregnancy Category C mean?
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Does fluoxetine affect fertility?
Fluoxetine, in particular, has been the subject of multiple studies and has been associated with gonadotoxic effects, including decreased sperm concentration and motility, increased deoxyribonucleic acid fragmentation, and decreased reproductive organ weights.
What is the safest antidepressant for pregnancy?
Antidepressants that are considered safer include:
- Fluoxetine (Prozac, Sarafem)
- Citalopram (Celexa)
- Sertraline (Zoloft)
- Amitriptyline (Elavil)
- Desipramine (Norpramin)
- Nortriptyline (Pamelor)
- Bupropion (Wellbutrin)
What is autism caused by?
There is no known single cause for autism spectrum disorder, but it is generally accepted that it is caused by abnormalities in brain structure or function. Brain scans show differences in the shape and structure of the brain in children with autism compared to in neurotypical children.
Can anxiety during pregnancy cause autism?
In humans, research has long shown that maternal stress during pregnancy prompts systemic inflammation in both the mother and fetus and is a risk factor for autism, said senior author Daniel Barth, a professor of psychology and neuroscience.
What can you take for anxiety when your pregnant?
Selective serotonin reuptake inhibitors (SSRIs) are commonly prescribed for depression and anxiety during pregnancy and after delivery.
When should you stop taking medication when pregnant?
Overview. Doctors usually tell women to avoid medicines during pregnancy, if possible, especially during the first 3 months. That is when a baby’s organs form. But sometimes you have to take medicine to treat a health problem, such as high blood pressure or asthma.
Can antidepressants cause miscarriage?
Conclusions: Antidepressant use in the first trimester is associated with an increased risk of miscarriage when compared with either nondepressed or depressed unexposed women, even after accounting for induced abortions.