Does grapefruit affect Zoloft?

Anti-anxiety medications such as sertraline (Zoloft), buspirone (Buspar), and diazepam (Valium) can cause drowsiness or dizziness when taken with grapefruit juice.

Why should I avoid grapefruit while taking sertraline?

Grapefruit interferes with proteins in the small intestine and liver that normally break down many medications. Eating grapefruit or drinking grapefruit juice while taking these medications can lead to higher levels of them in your blood — and more side effects.

Does Citrus affect Zoloft?

No interactions were found between lemon and Zoloft.

What should you not take with Zoloft?

Avoid taking MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before and after treatment with this medication.

What happens if you eat grapefruit on Ssris?

“There’s huge variation in the amount of enzyme people have in their guts. Fooling around with grapefruit juice is not a good idea.” Grapefruit juice can also interfere with the metabolism of selective serotonin reuptake inhibitors, or S.S.R.I.’s, like Prozac, which are used to treat depression.

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How much grapefruit juice causes a drug interaction?

One whole grapefruit or 200 mL of grapefruit juice is sufficient to cause clinically relevant increased systemic drug concentration and subsequent adverse effects. Seville oranges, (often used in marmalades), limes and pomelos also produce this interaction.

How long after eating grapefruit can I take medication?

This makes it more likely that you will have side effects from the medicine. Interactions can happen up to three days after eating or drinking grapefruit. This means you cannot drink grapefruit juice in the morning and take your medications later in the day to stop possible medicine interactions.

Can you eat grapefruit while taking Paxil?

Grapefruit, grapefruit juice, and cranberry juice may cause the clomiPRAMINE levels in your body to increase. This may lead to potentially dangerous adverse effects.

Should you take Zoloft with food?

Administer once daily either morning or evening. If Zoloft makes you drowsy, take it at bedtime. May be taken with or without food; however, this needs to be consistent.

Why do you gain weight on sertraline?

It’s also possible that sertraline and other SSRIs may block the effects of hormones that control sodium and fluid in your body, resulting in fluid retention. In short, while weight gain is a known side effect of sertraline and several other antidepressants, experts aren’t yet completely sure why.

Will Zoloft cause weight loss?

SSRIs may cause weight loss with short-term use, but taking them for 6 months or more can lead to an increase in weight. Your doctor will discuss benefits, risks, and side effects before you start any new medication. This includes weight-related side effects of antidepressants.

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Why is Zoloft bad for you?

Taking Zoloft may put you at risk for a rare, possibly life-threatening condition called serotonin syndrome. This risk is higher if you are also taking other serotonin-related medications like triptans (a common migraine medication), tricyclic antidepressants, or the pain medication Ultram (tramadol).

Does Zoloft change your personality?

Medication can definitely change people’s personalities, and change them quite substantially. Paxil is rarely prescribed now, because of concerns about side effects and withdrawal, says Tang, but other SSRIs (such as Prozac and Zoloft) are likely to have the same effect on personality.

Why does grapefruit affect medication?

Many drugs are broken down (metabolized) with the help of a vital enzyme called CYP3A4 in the small intestine. Grapefruit juice can block the action of intestinal CYP3A4, so instead of being metabolized, more of the drug enters the blood and stays in the body longer.

Can I drink alcohol with sertraline?

You can drink alcohol while taking sertraline, but it may make you feel sleepy. It might be best to stop drinking alcohol until you see how the medicine makes you feel.

What are the symptoms of serotonin syndrome?

Symptoms

  • Agitation or restlessness.
  • Confusion.
  • Rapid heart rate and high blood pressure.
  • Dilated pupils.
  • Loss of muscle coordination or twitching muscles.
  • Muscle rigidity.
  • Heavy sweating.
  • Diarrhea.