Even at lower doses, trazodone can cause you to feel relaxed, tired, and sleepy. It does this by blocking chemicals in the brain that interact with serotonin and other neurotransmitters, such as, 5-HT2A, alpha1 adrenergic receptors, and H1 histamine receptors.
How long does the drowsiness from trazodone last?
At these low doses, trazodone induces and maintains sleep without causing daytime drowsiness or tolerance, mainly because of its short half-life (3–6 hours).
Does trazodone get you sleepy?
Trazodone can make you feel sleepy. If you take it once a day, it’s best to take it in the evening or before you go to bed. If you and your doctor decide to take you off trazodone, your doctor will probably recommend reducing your dose gradually to help prevent extra side effects.
Is trazodone a strong sleeping pill?
Because of the chemical composition of trazodone, it has been found to have mild sedating effects, and it is less effective than other antidepressants for the treatment of depression. Therefore, trazodone has found greater utility as a sleep aid than it has as an antidepressant medication.
How long before going to bed should I take trazodone?
Precautions If You Take Trazodone
If you have trouble getting to sleep, take it several hours before you go to bed. If you have trouble staying asleep, take it within 30 minutes of bedtime.
Does trazodone make you groggy in the morning?
Trazodone usage can cause a decrease in sodium levels in the body, a disruption of the nervous system or serotonin syndrome. The most common side effects include: Drowsiness (including feeling groggy the next day)
What is better than trazodone for sleep?
The study found Ambien to be more effective than trazodone. The American Academy of Sleep Medicine Clinical guidelines recommend the following: Trazodone: “We suggest that clinicians not use trazodone as a treatment for sleep onset or sleep maintenance insomnia (versus no treatment) in adults.”
Which is better for sleep trazodone or melatonin?
Conclusions: This study demonstrated that both melatonin and trazodone would improve SQ in outpatients with MDD after 8 weeks of treatment with sertraline. However, melatonin created greater reduction in SL than trazodone did after the first 4 weeks of use.
How much is too much trazodone for sleep?
Doctors often recommend a daily dose of 150 mg of trazodone for depression treatment. This amount can be increased to upward of 600 mg if necessary. Much lower doses are used to treat insomnia. As such, any amount exceeding 600 mg in 24 hours is considered an overdose.