Does Zoloft cause kidney problems?

For people with kidney problems: If you have kidney problems or a history of kidney disease, you may not be able to clear this drug from your body well. This may increase the levels of this drug in your body and cause more side effects. This drug may also decrease your kidney function, making your kidney disease worse.

Is sertraline safe for kidneys?

Meaning Sertraline may not be an effective treatment for major depressive disorder in patients with non–dialysis-dependent chronic kidney disease. Importance Major depressive disorder (MDD) is prevalent among patients with chronic kidney disease (CKD) and is associated with morbidity and mortality.

What are the most serious risks of taking Zoloft?

Nausea, dizziness, drowsiness, dry mouth, loss of appetite, increased sweating, diarrhea, upset stomach, or trouble sleeping may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

Do antidepressants cause kidney problems?

A: Any medication, if taken without consultation with your physician, can cause kidney damage. It is frequently combinations of medication, both prescribed and over the counter that cause kidney damage.

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Can you take Zoloft if you have kidney disease?

Sertraline may not be an effective treatment for major depressive disorder in patients with non–dialysis-dependent chronic kidney disease.

Does SSRI cause kidney problems?

Increased bleeding risk was reported in association with serotonin-selective reuptake inhibitors (SSRIs),29 which may become problematic in advanced CKD and underlying platelet dysfunction related to uremia.

Is Serotonin bad for kidneys?

Serotonin (5HT) has significant effects on renal metabolism and glomerular function and is a potent renal vasoconstrictor.

Why is Zoloft bad for you?

Taking Zoloft may put you at risk for a rare, possibly life-threatening condition called serotonin syndrome. This risk is higher if you are also taking other serotonin-related medications like triptans (a common migraine medication), tricyclic antidepressants, or the pain medication Ultram (tramadol).

Is 50mg of Zoloft a lot?

The maximum dose of Zoloft is 200 mg per day (which can be taken as two 100 mg tablets). Most studies suggest that the most effective dose of Zoloft is 50 mg per day. This dose is proven to be the most effective and tolerable dose for most patients.

Why should you not take sertraline on a night?

Sertraline’s effectiveness doesn’t depend on the time it’s taken, but your sleep schedule may be better if you take it at a certain time of day. For some people, sertraline can make you feel tired and sleepy. For others, sertraline can cause insomnia or difficulty sleeping.

What are the signs that something is wrong with your kidneys?

Signs of Kidney Disease

  • You’re more tired, have less energy or are having trouble concentrating. …
  • You’re having trouble sleeping. …
  • You have dry and itchy skin. …
  • You feel the need to urinate more often. …
  • You see blood in your urine. …
  • Your urine is foamy. …
  • You’re experiencing persistent puffiness around your eyes.
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What medications can harm kidneys?

Many medicines can cause acute kidney injury (acute renal failure), such as:

  • Antibiotics. …
  • Some blood pressure medicines. …
  • Medicines used for cancer treatment (chemotherapy). …
  • Dyes (contrast media). …
  • Illegal drugs. …
  • Medicines used to treat HIV. …
  • Nonsteroidal anti-inflammatory drugs. …
  • Ulcer medicines.

How do you improve kidney function?

Here are some tips to help keep your kidneys healthy.

  1. Keep active and fit. …
  2. Control your blood sugar. …
  3. Monitor blood pressure. …
  4. Monitor weight and eat a healthy diet. …
  5. Drink plenty of fluids. …
  6. Don’t smoke. …
  7. Be aware of the amount of OTC pills you take. …
  8. Have your kidney function tested if you’re at high risk.

What is the best antidepressant for kidney disease?

Selective serotonin reuptake inhibitors (SSRIs): These are the most commonly prescribed and studied anti-depressants for patients with ESRD (16). They are protein-bound, metabolized by the liver, and unlikely to be removed by dialysis (14).

What antidepressants can you take with kidney disease?

Many older patients have chronic kidney disease (CKD), and a lower dose of anti-depressants paroxetine, mirtazapine and venlafaxine is recommended in patients with CKD to prevent drug accumulation from reduced elimination.

What are the side effects of Zoloft?

What Are The Possible Side Effects Of Sertraline?

  • Headache, nausea, diarrhea, dry mouth, increased sweating.
  • Feeling nervous, restless, fatigued, sleepy or having trouble sleeping (insomnia)