Is ephedrine acid or base?

It is a conjugate base of a (-)-ephedrinium. Ephedrine was first described in western literature in 1888, as a naturally occurring component of the ephedra plant, along with [pseudoephedrine].

What is the pH of ephedrine?

The pH range is 4.5 to 7.0. Ephedrine sulfate is a sympathomimetic amine that directly acts as an agonist at α- and ß adrenergic receptors and indirectly causes the release of norepinephrine from sympathetic neurons.

What class is ephedrine?

Ephedrine belongs to a class of drugs called Alpha/Beta Adrenergic Agonists.

Is ephedrine sulfate a base?

Each mL contains ephedrine sulfate, USP 5 mg (equivalent to 3.8 mg ephedrine base), 0.9% sodium chloride, USP in water for injection. The pH is adjusted with sodium hydroxide and/or glacial acetic acid if necessary.

Storage And Handling.

NDC Presentation
14789-250-10 10 mL vials packaged in a carton of 10

Is ephedrine water soluble?

It exists as colorless crystals or white, crystalline, orthorohombic needless or powder, odorless, with a bitter taste. It is freely soluble in four parts of water, and in 17 parts of alcohol, very slightly soluble in chloroform and practically insoluble in ether.

Is Ephedrine a weak acid?

Because many drugs are either weak acids or weak bases and have limited water solubility, they are often used as their “salts” to increase their aqueous solubility. … Also, a salt such as ephedrine hydrochloride can be prepared between a weak base-ephedrine and a strong acid-hydrochloric acid.

IMPORTANT:  Best answer: What time should I take Ritalin?

What functional groups are in ephedrine?

Ephedrine contains an arene (the aromatic benzene ring), an alcohol (the -OH group), an amine (the nitrogen-based group), and an N-methyl group (-CH3 attached to nitrogen). It does not contain a ketone (C=O), or any other carboxyl groups.

Is Ephedrine a sympathomimetic?

Ephedrine is one of the most commonly used sympathomimetic drugs in the practice of anesthesia (1). Its stimulant actions result from direct and indirect activation of α- and β-adrenoceptors (2,3).

Is ephedrine a controlled substance?


Ephedrine products are usually not categorized as controlled substances internationally. To prevent ephedrine products from being illegally transformed into the amphetamine and/or its analogs, these products are usually packaged and supplied in the limited quantities, and cannot be openly displayed in pharmacies.

What is Ephedrine HCL?

Ephedrine hydrochloride is an alkylbenzene. ChEBI. A phenethylamine found in EPHEDRA SINICA. PSEUDOEPHEDRINE is an isomer. It is an alpha- and beta-adrenergic agonist that may also enhance release of norepinephrine.

Is Ephedrine a vasopressor?

Background: Historically, ephedrine has been the vasopressor of choice for treatment of most cases of hypotension in obstetric patients. However, the choice of vasopressor in the parturient receiving a beta-adrenergic agent for tocolysis has not been evaluated extensively.

Is ephedrine and epinephrine the same?

As a vasoconstrictor, epinephrine is 100 to 1,000 times more potent than ephedrine. 1 Mix-ups between these two drugs have resulted in serious patient harm.

Is ephedrine sulfate a stimulant?

Ephedrine is a medication and stimulant. It is often used to prevent low blood pressure during anesthesia. It has also been used for asthma, narcolepsy, and obesity but is not the preferred treatment.

IMPORTANT:  Best answer: Can Abilify 5 mg be cut in half?

What is ephedrine soluble in?

Soluble in water, in alcohol, in chloroform, and in ether; moderately and slowly soluble in mineral oil, the solution becoming turbid if the Ephedrine contains more than about 1% of water. Ephedrine Hydrochloride: Fine, white, odorless crystals or powder.

Is ephedrine polar?

The no-polar structure of ephedrine makes this substance more liposoluble than catecholamines. It is thermodynamically more stable, in consequence, it is not a substrate for monoamineoxidase (MAO) or the catechol-O-methyltranspherase.

How is ephedrine made?

Natural ephedrine is prepared by extraction from Ephedra plants. This process is typically employed for ephedrine manufactured in China. Semi-synthetic ephedrine is prepared by fermentation of sugar followed by amination, a process known to be used in India. Fully chemically synthesized ephedrine is produced elsewhere.