Long-acting risperidone is the first atypical antipsychotic available in a formulation which offers a sustained, steady release of drug and is thus an attractive, new option in the treatment of patients with schizophrenia.
Is risperidone short or long-acting?
Summary: Risperidone is the first atypical antipsychotic available in a long-acting injectable formulation. After a single injection, significant plasma levels of the drug are achieved at week 3 and sustained through week 6, subsiding by weeks 7-8.
How long is risperidone effective for?
The medication effects last for approximately 2 weeks. If you are new to taking Risperdal Consta® (risperidone long-acting injection), your health care provider may want you to take the tablet form or risperidone daily for up to 3 weeks. Perseris® (risperidone long-acting injection) should be received every month.
What is the peak time for risperidone?
Following oral administration of solution or tablet, mean peak plasma concentrations of risperidone occurred at about 1 hour. Peak concentrations of 9-hydroxyrisperidone occurred at about 3 hours in extensive metabolizers, and 17 hours in poor metabolizers.
Does risperidone have a long half life?
Risperidone, sold under the brand name Risperdal among others, is an atypical antipsychotic used to treat schizophrenia and bipolar disorder.
|Bioavailability||70% (by mouth)|
|Metabolism||Liver (CYP2D6 mediated to 9-hydroxyrisperidone)|
|Elimination half-life||20 hours (by mouth), 3–6 days (IM)|
What are the side effects of Risperdal?
Drowsiness, dizziness, lightheadedness, drooling, nausea, weight gain, or tiredness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Dizziness and lightheadedness can increase the risk of falling. Get up slowly when rising from a sitting or lying position.
Is invega the same as risperidone?
Paliperidone (Invega) is a metabolite of risperidone (Risperidone). While the efficacy and side effects of these medications are similar, there are some difference in 5-HT2A/D2 (serotonin/dopamine) binding ratios. The risperidone binding ratio is lower than the paliperidone binding ratio.