Conclusion. Both St John’s wort extract and SSRIs are effective in treating mild-to-moderate depression. St John’s wort extract is safer than SSRIs.
Is St John’s wort as effective as antidepressants?
Studies show that St. John’s wort can be as effective as antidepressants in treating mild to moderate depression — and has fewer side effects. Additionally, some evidence supports its use for the treatment of PMS, wound healing and symptoms of menopause.
Should I try St John’s wort before antidepressants?
Don’t combine St John’s wort and prescription antidepressants such as SSRIs. That can cause a problem of too much serotonin, called serotonin syndrome. You may have to wait a period of time before you start St.
Does St John’s wort work like an SSRI?
John’s wort may reduce symptoms in people with mild-to-moderate, but not severe (or major) depression. In many studies it seems to work as well as selective serotonin reuptake inhibitors (SSRIs), a popular type of antidepressant often prescribed to treat depression.
Is St Johns Wort bad for you?
Safety and side effects
When taken orally for up to 12 weeks in appropriate doses, St. John’s wort is generally considered safe. However, it may cause: Agitation and anxiety.
Can St John’s wort cause anxiety?
At recommended doses, St. John’s wort generally does not cause side effects. Uncommon side effects of St. John’s wort include anxiety, dry mouth, sensitivity to sunlight, dizziness, stomach upset, headache, sexual problems, and fatigue.
Is serotonin an antidepressant?
SSRI antidepressants are a type of antidepressant that work by increasing levels of serotonin within the brain. Serotonin is a neurotransmitter that is often referred to as the “feel good hormone”.
Can you take St John’s wort long term?
Therefore, St. John’s wort extract ZE 117 is a safe and effective way to treat mild to moderate depression over long periods of time, and therefore seems especially suitable for a relapse prevention.
Can St John’s wort make you feel worse?
They may include upset stomach, dry mouth, headache, fatigue, dizziness, confusion, sexual dysfunction, or sensitivity to sunlight. Also, St. John’s wort is a stimulant and may worsen feelings of anxiety in some people.
What medication should you not take with St John’s wort?
There are also reasonable grounds for concern that St John’s Wort may reduce the efficacy of the following medicines:
- other HIV protease inhibitors (saquinavir, ritonavir, nelfinavir)
- HIV non-nucleoside reverse transcriptase inhibitors (efavirenz, nevirapine, delavirdine)
Why does St John’s wort interfere with everything?
St. John’s wort can cause serious interactions with commonly used medications because of how it gets broken down by the liver. The herb can interact with medication in different ways. It can make some drugs less effective while making the effect of others stronger.
Should I take St John’s wort in the morning or night?
It can cause some side effects such as trouble sleeping, vivid dreams, restlessness, anxiety, irritability, stomach upset, fatigue, dry mouth, dizziness, headache, skin rash, diarrhea, and tingling. Take St. John’s wort in the morning or lower the dose if it seems to be causing sleep problems. St.
Is St John’s wort safe to take everyday?
A normal dose range would be anywhere from 300 to 1200 mg a day. It’s usually taken in divided doses (300 mg three times daily or 600 mg twice daily). The effects of St. John’s wort on the body are not fully understood.
How much St John’s wort is safe?
John’s wort is likely safe when used in doses up to 900 mg daily for up to 12 weeks. It can cause some side effects such as diarrhea, dizziness, trouble sleeping, restlessness, and skin tingling. St. John’s wort interacts with many drugs.
How much St John’s wort should I take for anxiety?
In studies2 of social anxiety disorder, the typical dosage ranges from 600 to 1800 milligrams of St. John’s Wort daily. However, because ingredients can vary, doses may also vary.