There is a known drug interaction between sertraline and grapefruit juice; when they are taken together, there is an increased risk of side effects or toxicity from the sertraline. The patient was advised to discontinue his sertraline for a few days.
Why can’t you eat grapefruit on sertraline?
Grapefruit interferes with proteins in the small intestine and liver that normally break down many medications. Eating grapefruit or drinking grapefruit juice while taking these medications can lead to higher levels of them in your blood — and more side effects.
Can I eat grapefruit while taking sertraline?
Anti-anxiety medications such as sertraline (Zoloft), buspirone (Buspar), and diazepam (Valium) can cause drowsiness or dizziness when taken with grapefruit juice.
Why do some medications say no grapefruit?
Many drugs are broken down (metabolized) with the help of a vital enzyme called CYP3A4 in the small intestine. Grapefruit juice can block the action of intestinal CYP3A4, so instead of being metabolized, more of the drug enters the blood and stays in the body longer.
How long should you wait to eat grapefruit after taking medication?
This makes it more likely that you will have side effects from the medicine. Interactions can happen up to three days after eating or drinking grapefruit. This means you cannot drink grapefruit juice in the morning and take your medications later in the day to stop possible medicine interactions.
What can’t you eat on sertraline?
Avoid cola drinks, chocolate and caffeine containing food items with sertraline since the combination can result in a condition called serotonin syndrome with symptoms of high fever, agitation, vomiting, nausea, rapid heartbeat, trembling, sweating and weird movements on the muscles.
Can you drink alcohol when on sertraline?
You can drink alcohol while taking sertraline, but it may make you feel sleepy. It might be best to stop drinking alcohol until you see how the medicine makes you feel.
Does caffeine affect sertraline?
No interactions were found between caffeine and sertraline.
Can sertraline cause weight gain?
What medications cause weight gain? Antipsychotic drugs, antidepressants , and mood stabilizers are common drugs that have the most potential to increase weight gain. All 12 of the leading antidepressants, including fluoxetine (Prozac), sertraline (Zoloft), and escitalopram (Lexapro), make gaining weight more likely.
Can you eat grapefruit with hydrochlorothiazide?
Drug and food interactions
Grapefruit juice can significantly increase the blood levels and effects of medications like felodipine. You may be more likely to experience side effects such as headache, low blood pressure, irregular heartbeat, swelling, and fluid retention.
What are the side effects of sertraline?
Sertraline may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
- difficulty falling asleep or staying asleep.
- dry mouth.
- loss of appetite.
What is serotonin syndrome?
Serotonin syndrome is a condition that happens when there is too much serotonin in the body. This can be caused by medications that impact serotonin levels. Antidepressants are linked to this condition.
What medication can you not eat grapefruit with?
Examples of common medications that interact with grapefruit juice include certain statin cholesterol drugs such as atorvastatin (Lipitor), lovastatin, simvastatin (Zocor), felodipine (Plendil) and other calcium channel blockers, clarithromycin (Biaxin), and loratadine (Claritin).
How much grapefruit juice causes a drug interaction?
One whole grapefruit or 200 mL of grapefruit juice is sufficient to cause clinically relevant increased systemic drug concentration and subsequent adverse effects. Seville oranges, (often used in marmalades), limes and pomelos also produce this interaction.
Why grapefruit is bad for you?
So why is grapefruit getting a bad rap? Grapefruit juice inhibits a chemical in the intestine needed to break down many drugs in the body. The absence of this chemical can lead to higher blood levels. In effect, the drug becomes more potent.
Why is grapefruit bad for high blood pressure?
Grapefruit contains compounds that may interfere with how your body absorbs some drugs, including some blood pressure medicines. It can leave too much or too little of the drug in your bloodstream, which may be dangerous.