Quick Answer: What is the most tolerated SSRI?

Overall, citalopram appears to be the best-tolerated SSRI, followed by fluoxetine, sertraline, paroxetine, and fluvoxamine. The latter 2 drugs are associated with the most side effects and the highest discontinuation rates because of side effects in clinical trials.

What is the most tolerated antidepressant?

Bupropion, citalopram, escitalopram, and sertraline were better tolerated than the other antidepressants. Escitalopram and sertraline were found to have the best combination of efficacy and acceptability. Efficacy results.

Which class of antidepressants have the least side effects?

Selective serotonin reuptake inhibitors (SSRIs).

These medications generally cause fewer bothersome side effects and are less likely to cause problems at higher therapeutic doses than other types of antidepressants are.

What is the best antidepressant for anxiety with the least side effects?

Tricyclic antidepressants

Tricyclic antidepressants (TCAs) are an older class of antidepressant drug. Although they may be effective for the treatment of depression and anxiety, doctors often prescribe SSRIs instead, as they cause fewer side effects.

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What is the number 1 SSRI?

Prozac (fluoxetine): Prozac is still one of the most popular SSRIs in the United States. It’s one of the only ones that the FDA has approved for children and teenagers to use. The 2017 antidepressant use study found that a little over 11% of respondents reported taking Prozac for depression.

What is the safest antidepressant for anxiety?

As of this writing, some of the anxiety medications with the fewest reported side effects and least risk of side effects include:

  • Most Benzodiazepines (Xanax, Valium)
  • Bupropion (Wellbutrin)
  • Citalopram (Celexa – SSRI)
  • Paroxetine (Paxil – SSRI)

What is the best SSRI for anxiety?

The only SSRIs that are currently FDA-approved for this condition are sertraline (Zoloft) and immediate- and extended-release paroxetine (Paxil, Paxil CR). Extended-release venlafaxine (Effexor XR) — a serotonin and norepinephrine reuptake inhibitor (SNRI) — is also FDA-approved to treat social anxiety disorder.

Which SSRI has least GI side effects?

Escitalopram and sertraline were shown to be the least tolerated antidepressants on the gastrointestinal tract, being associated with all the considered SEs with the exception of constipation and increased appetite, while mirtazapine was shown to be the antidepressant with fewer side effects on the gut, being only …

Which SSRI causes least weight gain?

Bupropion was associated with the least amount of weight gain, close to none. Two others that also appeared to have less weight gain were amitriptyline and nortriptyline. Amitriptyline and nortriptyline are older drugs. Because newer drugs tend to have fewer side effects, those two aren’t prescribed as frequently.

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Is cipralex safe?

To date, there are no known problems associated with long term use of escitalopram. It is a safe and effective medication when used as directed.

What is the 3 3 3 rule for anxiety?

Follow the 3-3-3 rule.

Look around you and name three things you see. Then, name three sounds you hear. Finally, move three parts of your body — your ankle, fingers, or arm.

Which SNRI is best for anxiety?

Serotonin-norepinephrine reuptake inhibitors, also known as SNRIs, are a new class of drugs used to relieve depression and anxiety.

These are the most commonly prescribed SNRI medications for anxiety:

  • Effexor (venlafaxine)
  • Pristiq (desvenlafaxine)
  • Cymbalta (duloxetine)

What is the first drug of choice for anxiety?

Selective serotonin reuptake inhibitors (SSRIs) are currently considered the first-line medication for most forms of anxiety.

Is Lexapro better than Prozac?

When comparing Lexapro to Prozac, the authors found both drugs to be similarly effective. Another study, which was a review of many studies, compared antidepressants and initially found Lexapro to possibly be more effective and better tolerated than other antidepressants.

What is the best antidepressant for energy and motivation?

Prozac/Fluoxetine

It gives people more energy than other antidepressants which may not work well for someone with insomnia as well as depression. That being said, for those with low energy, it can be helpful. Fluoxetine treats many mental health issues which includes depression, OCD, and panic disorders.