What is depot antipsychotic medication? It is a special preparation of the medication, which is given by injection. The medication is slowly released into the body over a number of weeks.
What antipsychotics can be given as depot?
Antipsychotic depot injections
|Antipsychotic depot injections||Preparations|
|Flupentixol decanoate||20mg/ml, 40mg/2ml, 50mg/0.5ml, 100mg/1ml, 200mg/ml injection|
|Haloperidol decanoate||50mg/ml, 100mg/ml injection|
|Paliperidone palmitate 1-monthly(Xeplion®)||50mg, 75mg, 100mg, 150mg pre-filled syringes|
What does a depot injection do?
A depot injection is a term for an injection formulation of a medication which releases slowly over time to permit less frequent administration of a medication. They are designed to increase medication adherence and consistency, especially in patients who commonly forget to take their medicine.
Why are depot antipsychotics used?
Depot Antipsychotics are used to treat schizophrenia, psychosis and similar conditions. With schizophrenia, many people hear voices talking to them or about them. They may also become suspicious or paranoid. Some people also have problems with their thinking and feel that other people can read their thoughts.
How long does a depot injection last?
The contraceptive injection (Depo-Provera, Sayana Press or Noristerat) releases the hormone progestogen into your bloodstream to prevent pregnancy. Depo-Provera is most commonly given in the UK and lasts for 13 weeks.
What is the strongest antipsychotic drug?
Clozapine, which has the strongest antipsychotic effect, can cause neutropenia. A problem in the treatment of schizophrenia is poor patient compliance leading to the recurrence of psychotic symptoms.
How often are depot injections given?
How are depot injections given? Injections are usually given every two, three or four weeks, depending on the drug. Certain antipsychotics may last for longer periods when given as a depot injection. Your injection will usually be given by a healthcare professional in a community setting.
How long do antipsychotic injections last?
They change how some of your brain chemicals act. But since you take them every 2 to 4 weeks (or sometimes even as long as every 3 months) instead of every day, the medicine stays in your body longer. These antipsychotic drugs come in a long-lasting form: Aripiprazole (Abilify Maintena)
How do you administer antipsychotic depot?
Most oil-based depot antipsychotic injections must be administered only into the gluteal muscle by deep intramuscular (IM) injection. The exceptions to this are flupentixol and zuclopenthixol depots which are also licensed to be administered via the lateral thigh.
What do antipsychotics do?
How do antipsychotics work? Antipsychotic drugs don’t cure psychosis but they can help to reduce and control many psychotic symptoms, including: delusions and hallucinations, such as paranoia and hearing voices. anxiety and serious agitation, for example from feeling threatened.
How is depot injection given?
What happens when the nurse or doctor gives the depot injection? You go into a private room with the nurse or doctor. The injection is usually given into the buttock. After each injection the medicine stays in your body for a few weeks.
Do depot injections hurt?
Conclusion: Depot injections are painful. The pain they inflict has a typical course, and medication type is among the factors that influence this pain. This pain might have an effect on patients’ attitude toward depot injections and thus is of importance in the management of patients suffering from schizophrenia.
What do antipsychotics do to a normal person?
Side-effects of typical antipsychotics vary depending on the drug and may include drowsiness, agitation, dry mouth, constipation, blurred vision, emotional blunting, dizziness, stuffy nose, weight gain, breast tenderness, liquid discharge from breasts, missed periods, muscle stiffness or spasms.
What is paliperidone depot?
Paliperidone extended-release injections (Invega Sustenna, Invega Trinza) are used to treat schizophrenia (a mental illness that causes disturbed or unusual thinking, loss of interest in life, and strong or inappropriate emotions).
What is depot clinic?
A depot injection is a long-acting form of medication. The nurse injects the medication into your muscle where it forms a store or ‘depot’. This is then released slowly into your body over a period of weeks.
What happens when you take antipsychotics and don’t need them?
If you decide to come off antipsychotics your doctor will help you come off the medication gradually by reducing the dose over a period of time. If you stop antipsychotics suddenly it can cause ‘rebound psychosis’. This means that the symptoms of your illness return suddenly, and you may become unwell again.