Both Effexor and Wellbutrin can treat symptoms of depression. However, Effexor is a serotonin-norepinephrine reuptake inhibitor (SNRI) and Wellbutrin is an aminoketone. Therefore, these drugs work in different ways. They also have different FDA-approved uses.
Is bupropion an SSRI or SNRI?
Most antidepressants are selective serotonin reuptake inhibitor (SSRI). They boost the levels of serotonin in the brain. Bupropion, or Wellbutrin, is different. It is a norepinephrine-dopamine reuptake inhibitor (NDRI).
What class of drug is Wellbutrin?
Wellbutrin is a prescription medicine used to treat the symptoms of major depression and seasonal affective disorder. Wellbutrin may be used alone or with other medications. Wellbutrin belongs to a class of drugs called Antidepressants, Dopamine Reuptake Inhibitors, Antidepressants, Other, Smoking Cessation Aids.
What antidepressants are in the same class as Wellbutrin?
- Bupropion (Wellbutrin SR, Wellbutrin XL, others)
- Mirtazapine (Remeron)
- Vilazodone (Viibryd)
- Vortioxetine (Trintellix)
Which drugs are SNRIs?
The Food and Drug Administration (FDA) has approved these SNRIs to treat depression:
- Desvenlafaxine (Pristiq)
- Duloxetine (Cymbalta) — also approved to treat anxiety and certain types of chronic pain.
- Levomilnacipran (Fetzima)
- Venlafaxine (Effexor XR) — also approved to treat certain anxiety disorders and panic disorder.
Who should not take Wellbutrin?
You should not take Wellbutrin if you are allergic to bupropion, or if you have:
- a seizure disorder;
- an eating disorder such as anorexia or bulimia; or.
- if you have suddenly stopped using alcohol, seizure medications, or a sedative (such as Xanax, Valium, Fiorinal, Klonopin, and others).
Does Wellbutrin cause blood clots?
It can cause embolisms (blood clots) or abscesses in the veins or at the site of injection,” he says. Dr. James Truong, an emergency medicine physician in North Bay, Ont. recently made a presentation about the Wellbutrin-injecting drug users he’s seeing at his hospital.
Why was Wellbutrin discontinued?
The decision is based on an FDA study that found that the extended release (XL) form of bupropion — Budeprion XL — at the 300 milligram (mg) dose was not bioequivalent to brand-name Wellbutrin XL at the same dose, suggesting that it may not be as safe and effective.
What are the worst side effects of Wellbutrin?
Serious side effects of Wellbutrin
- Worsened depression.
- Suicidal thoughts and behaviors.
- Homicidal thoughts.
- Neuropsychiatric events (psychosis, mania, hallucinations, and panic attacks)
- Severe high blood pressure (hypertension)
- Heart problems, including irregular heartbeat.
- Angle-closure glaucoma.
Is Wellbutrin good for anxiety?
Wellbutrin XL has been shown in one clinical trial to be as effective for anxiety as escitalopram (Lexapro), a common antidepressant doctors prescribe for patients with anxiety. Some research also suggests Wellbutrin can help mitigate anxiety symptoms related to depression.
What’s better Effexor or Wellbutrin?
Effexor and Wellbutrin are both effective drugs that treat depression. Effexor is better than Wellbutrin for treating anxiety disorders that are experienced alongside depression. However, compared to Wellbutrin, Effexor may cause more sexual side effects, such as abnormal ejaculation and impotence.
How long can you stay on Wellbutrin?
Some people take them for a few weeks or months, whereas others take them for years. About one in four people on antidepressants have been taking them for 10 or more years. 1 Once they find an antidepressant that works for them, many people continue taking it indefinitely.
Why do doctors prescribe Lexapro and Wellbutrin together?
Wellbutrin and Lexapro affect different neurotransmitters and are oftentimes used together. The results of one clinical trial found that the use of both drugs together leads to significantly higher response and symptom remission rates as compared to typical monotherapy with SSRIs.
What is better for anxiety SSRI or SNRI?
SSRIs tend to be more commonly prescribed than SNRIs because they are effective at improving mood and tend to be less likely than some SNRIs to cause side effects. Other conditions that SSRIs are approved to treat, in addition to depression, include: Anxiety.
Which is better SSRI or SNRI?
The best medicine to treat depression varies from person to person. SNRIs tend to be more effective than SSRIs, but some people will find that SSRIs are more effective for them. A physician or psychiatrist can discuss your health history and symptoms to determine whether an SSRI or SNRI is best for you.
Which SNRI is best?
Milnacipran is the most balanced reuptake inhibitor among the current SNRIs, with nearly equipotent reuptake inhibition of serotonin and norepinephrine. According to some sources, milnacipran may even have slightly more noradrenergic effects than serotonergic effects—up to threefold higher.