What is an adverse effect of barbiturate administration?

Barbiturates may cause drowsiness, dizziness, lightheadedness, or decreased alertness. These side effects may be present the morning after taking a barbiturate at bedtime. Do not drive, use machines, or do anything else that could be dangerous until you know how barbiturates affect you.

Which is the major adverse effect of barbiturate?

When used according to instructions, the most common side effects of barbiturates are drowsiness, relaxation, and feeling sick. More serious side effects of barbiturate use may include: lack of coordination. headache.

What are contraindications to the administration of barbiturates?

Contraindications: Barbiturate sensitivity, liver disease, impaired renal function, patients with severe respiratory distress, respiratory disease in which dyspnea, obstruction or cor pulmonale is present, acute or chronic pain.

What are the signs of barbiturate poisoning?

Symptoms of barbiturate intoxication and overdose include:

  • Altered level of consciousness.
  • Difficulty in thinking.
  • Drowsiness or coma.
  • Faulty judgment.
  • Lack of coordination.
  • Shallow breathing.
  • Slow, slurred speech.
  • Sluggishness.
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What is barbiturate toxicity?

Barbiturate overdose is poisoning due to excessive doses of barbiturates. Symptoms typically include difficulty thinking, poor coordination, decreased level of consciousness, and a decreased effort to breathe (respiratory depression). Complications of overdose can include noncardiogenic pulmonary edema.

What is a major adverse side effect of barbiturate treatment for insomnia?

Barbiturates may cause drowsiness, dizziness, lightheadedness, or decreased alertness. These side effects may be present the morning after taking a barbiturate at bedtime.

What effects of barbiturate medication take effect within 15 40 minutes and last up to six 6 hours?

These barbiturates are Schedule III drugs. After oral administration, usually the onset of action starts within 15–40 min. The effect of these barbiturates may last up to 6 h. These drugs are used for treating insomnia and may also be used to achieve preoperative sedation.

Why are barbiturates contraindicated in porphyria?

ALA synthetase is involved in the porphyrin production pathway, and therefore barbiturates are contraindicated in patients with acute intermittent porphyria (AIP) or variegate porphyria because they may precipitate an attack, manifested by severe abdominal pain, nausea, vomiting, psychiatric disorders, and neurologic …

Which is a side effect of the Nonbenzodiazepine drug zolpidem?

In addition to their sleep-inducing effects, the nonbenzodiazepine sedatives may also induce dizziness, lightheadedness, confusion, double vision, and memory impairment. Other side-effects include nausea, ataxia, slurred speech, slow reflexes, loss of balance and coordination, and vertigo.

Which conditions are contraindicated for therapy with pyridostigmine?


  • asthma.
  • blockage of the stomach or intestine.
  • decreased kidney function.
  • a blockage in the urinary tract.
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What is the most serious risk in the acute use of barbiturates?

The most serious risks of barbiturate withdrawal include potential heart failure, seizures, suicidal thoughts, and sudden death.

What are side effects of benzodiazepines?

The most common side effects of benzodiazepines include:

  • drowsiness.
  • light-headedness.
  • confusion.
  • unsteadiness (especially in older people, who may fall and experience injuries)
  • dizziness.
  • slurred speech.
  • muscle weakness.
  • memory problems.

Which drug is used in barbiturate poisoning?

Sodium surital or sodium pentothal were the barbiturates used. The drug was administered intravenously in doses varying from 25 to 200 mg.

What is a barbiturate used for?

Barbiturates were first used in medicine in the early 1900s and became popular in the 1960s and 1970s as treatment for anxiety, insomnia, or seizure disorders. They evolved into recreational drugs that some people used to reduce inhibitions, decrease anxiety, and to treat unwanted side effects of illicit drugs.

What is a barbiturate level?

Barbiturates are sedatives/hypnotics used mainly for anesthesia and epilepsy treatment. They affect the gamma-aminobutyric acid (GABA) system and cause a CNS suppressive effect, which ranges from anxiolysis, sedation, and coma to fatal cardiovascular and respiratory arrest upon overdose.

What are the symptoms of central nervous system drug abuse?

Symptoms of severe CNS depression include:

  • reduced heart rate.
  • low breathing rate of fewer than 10 breaths per minute.
  • extreme confusion or memory loss.
  • nausea and vomiting.
  • poor judgment.
  • blue lips or fingertips.
  • irritability and aggression.
  • clammy or cold skin.